Anti-hyperglycaemic activity of ethanolic extract of Swertia chirayata and Trigonella Foenum graecum

Anti-hyperglycaemic activity of ethanolic extract of Swertia chirayata
and Trigonella Foenum graecum
Tomar V1., Kannojia P., Garud N., Garud A., Jain N
1Institute of Professional Studies, College of Pharmacy, Gwalior (M.P)
Abstract:
The main aim of the work was to focus the anti-hyperglycaemic activity of
Swertia chirayata leaves and Trigonella Foenum graecum seeds. These two plants are
widely used for the cure of diabetes from the time immemorial. The present study was to
evaluate the ethanolic extract of Trigonella Foenum graecum seeds and whole plant of
Swertia chirayata for its antihyperglycaemic activity in normal and alloxan induced
diabetic rats at the dose level of 250mg/kg. The animals were safe upto 2000mg/kg
confirmed by the acute and oral toxicity studies. Both the extracts showed a significant
reduction in blood glucose concentration. On the other hand, combined suspension of
extract of Swertia chirayata and Trigonella Foenum graecum showed minimum blood
glucose level on 7th day.